ea0056p292 | Cardiovascular Endocrinology and Lipid Metabolism | ECE2018
Buendia Richard
, Zambrano Monica
, Buendia Andres
, Vargas Tatiana
, Morales Alejandra
, Alejo Adriana
, Cardenas Santiago
, Mier Heidy
, Sanchez Diego
, Arrautt Johann
Background: Evidence has shown that the use of high doses of statins is associated with lower levels of LDL cholesterol and a decrease in cardiovascular events. Likewise, the use of high doses of statins may increase the risk of myopathy, elevation of liver enzymes, renal failure and cognitive alterations. We conducted a systematic review with a meta-analysis of all RCTs investigating the impact of atorvastatin and ezetimibe therapy on levels of LDL cholesterol vs high doses o...